Reese Witherspoon Grabs Jennifer Aniston's Butt at the Oscars: Watch!

She turned around, looking relieved to see the booty grabber was, in fact, her friend Reese. "Oh, hi, honey," Jen said with a laugh.

Ryan raised a hand to the air, exclaiming, "There was a grab! There was a grab!"

Jen raised both of her hands in the air. "I didn't do it," she said with a laugh. "So sorry!"

Of course, Jen and Ryan laughed it off, continuing their chat about her critically acclaimed Cake performance. The future Mrs. Justin Theroux has gotten handsy on a red carpet before herself, too—like when she grabbed co-star Jason Sudeikis' butt at the Horrible Bosses 2 premiere. She once even tweaked Kate Hudson's tuckus at the 2015 Golden Globes!