David Arquette Says Sister Alexis Does Not Identify as Transgender Anymore Sebastian Wright Published Apr 04, 2026 David Arquette Says Sister Alexis Does Not Identify as Transgender Anymore | Entertainment Tonight arrow-left-mobilearrow leftarrow-right-mobilearrow rightGroup 7Gallery Icon Copy 2Video Play Button Copy 5Hamburger MenuInstagramTwitterYoutubeShare Button7C858890-6955-48EA-B871-66CE1E33590CVideo-Playbutton Copy Skip to main content
